Depression That Hasn't Improved With Treatment
Major depressive disorder (MDD) doesn't always respond to the first medications tried. If other antidepressants haven't helped enough, SPRAVATO® (esketamine) nasal spray may be an option for eligible adults with treatment-resistant depression (TRD).
QuCiL Health™ is a SPRAVATO® REMS-certified center offering supervised, in-office treatment.
Not sure if this applies to you? An evaluation can help determine whether SPRAVATO® is appropriate for your situation.
Adults 18+ · REMS-certified center
Who SPRAVATO® Is For
SPRAVATO® is an FDA-approved prescription medicine used in adults 18 and older.
Approved Uses
Fast Relief in Treatment-Resistant Depression
Unlike conventional antidepressants that may take weeks to show meaningful results, clinical studies of SPRAVATO® have demonstrated improvements in depressive symptoms that can begin within 24 hours of the first treatment. For patients with severe depression, the ability to act quickly matters.
At QuCiL Health™ in Katy, Texas, we offer this treatment under the expert care of Shirley Amanfo, FNP-C, a REMS-certified provider. Our calm, monitored treatment room is designed for your comfort and safety.
FDA-Approved
Insurance-Covered
Fast-Acting
How SPRAVATO® Works
SPRAVATO® targets N-methyl-D-aspartate (NMDA) receptors in the brain — a completely different mechanism than traditional antidepressants that work on serotonin, norepinephrine, or dopamine systems.
Treatment is administered in our certified treatment room. Each session involves self-administration of the nasal spray under medical supervision, followed by a two-hour monitoring period to ensure your safety and comfort.
Your 4-Step Care Journey
From first evaluation to long-term support — here's what to expect at every step.
Initial Consultation & Evaluation
We review your medical history, previous treatments, current medications, and goals to determine whether SPRAVATO® is appropriate for you.
Session Scheduling & Administration
Once approved, we schedule your treatment sessions at convenient times. Each visit includes supervised self-administration in our calming treatment room.
Tailored Treatment Plan
Your plan is customized to your response and goals — beginning with the induction phase, transitioning to maintenance, then to ongoing care.
Ongoing Support
We monitor your progress throughout, adjust treatment as needed, and coordinate with your referring providers for continuity of care.
Your SPRAVATO® Treatment Phases
Treatment is delivered in three structured phases, adjusted to your response and needs.
Induction Phase
Week 1–4
Initial intensive phase to build therapeutic effect and establish a foundation for symptom relief and mood stabilization.
Maintenance Phase
Week 5–8
Consolidation phase to maintain progress, stabilize mood improvements, and prepare for long-term maintenance.
Ongoing Care
Week 9 onwards
Long-term maintenance with treatments every 1–2 weeks based on your individual response and ongoing needs.
Our SPRAVATO® treatment room — designed for comfort, privacy, and 2-hour observation.
Patient Video Testimonials
Hear from real patients about their experience with SPRAVATO® treatment at QuCiL Health.
Sarah's Story
Hear about her experience with SPRAVATO® treatment and the care she received at QuCiL Health.
Soraya's Story
Hear her perspective on SPRAVATO® treatment and the support she felt throughout her care.
Videos play directly on this page. Individual results vary.
What Our Patients Say
Real experiences from patients who found hope and healing with our care.
"At this clinic, they make you feel like a person and not just the next number. Very cordial medical staff that shows genuine concern and care. The Nurse Practitioner was knowledgeable, understanding, and truly listened to my concerns about my mental health."
"Mrs. Shirley took the time to address all my questions and concerns about my anxiety treatment. The entire experience, from the moment I walked in, was fantastic. I finally feel like I have a provider who understands what I'm going through."
"I have never felt this understood after a doctor's visit. Thank you for listening and providing such compassionate care. It's refreshing to find a provider who truly cares."
For Referring Providers
Psychiatrists, psychiatric nurse practitioners, therapists, and primary care providers can refer eligible patients for SPRAVATO® evaluation and treatment. We coordinate closely with your team and return the patient to your care once the SPRAVATO® treatment plan stabilizes.
Spravato withMe Patient Support Program
The Spravato withMe™ program offers personalized support for patients starting or continuing SPRAVATO® treatment — including insurance guidance, financial assistance information, and treatment-related resources.
Not Sure If SPRAVATO® Is Right for You?
An evaluation can help determine whether SPRAVATO® is appropriate for your situation.